|
T4327 |
Prexasertib dihydrochloride
|
LY2606368 (dihydrochloride),Prexasertib HCl,LY2606368 |
Apoptosis
,
Chk
,
S6 Kinase
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Prexasertib dihydrochloride (LY2606368) is an ATP-competitive CHK1 inhibitor (Ki: 0.9 nmol/L). in the cell-free assay, its IC50 values are 8 nM and 9 nM for CHK2 and RSK, respectively. |
|
T4310L |
Prexasertib lactate hydrate
|
Prexasertib monolactate monohydrate,LY-2606368,LY 2606368,LY2606368,Prexasertib monolactate monohydrate salt |
|
|
Prexasertib is an effective and selective Chk1/Chk2 inhibitor. Prexasertib causes Replication Catastrophe and Antitumor Effects through CHK1-Dependent Mechanisms. |
|
T4310L2 |
Prexasertib mesylate
|
LY-2606368,LY2606368,LY 2606368 |
|
|
Prexasertib is a potent and selective Chk1/Chk2 inhibitor. Prexasertib increases the effectiveness of conventional therapy in B-/T- cell progenitor acute lymphoblastic leukemia. LY2606368 causes replication catastrophe a... |
|
T63152 |
Prexasertib Mesylate Hydrate
|
|
|
|
Prexasertib Mesylate Hydrate (LY2606368 Mesylate Hydrate) is an ATP-competitive, selective, second generation cell cycle detection site kinase 1 (CHK1) inhibitor (IC50<1 nM, Ki: 0.9 nM). Prexasertib Mesylate Hydrate inhi... |
